| | Name | Platforms | Developer | Publisher | |
|---|
| Simple DL Series Vol. 9: The Misshitsu kara no Dasshutsu – Terebi Kyoku Mitchaku 24-ji Hen | 3DS | Intense | D3 Publisher | |
| Simple Dot | Steam | | | |
| Simple Early Build(0.1) | ItchIo | everythingwright34 | | |
| Simple FPS Aim Trainer | ItchIoSteam | TapHazardGames | | |
| Simple Farm | Steam | | | |
| Simple Fear | Steam | | | |
| Simple Galactic | ItchIo | arqcenick | | |
| Simple Game | ItchIo | CB Showtunes | | |
| Simple Goblin Game | ItchIo | officialgupta | | |
| Simple Hide-N-Seek! | ItchIo | Blazed Apps | | |
| Simple LOTO Simulator | Steam | | | |
| Simple Light Cycles | Steam | | | |
| Simple Little Wish | ItchIo | Nono Kros | | |
| Simple Machines | Steam | | | |
| Simple Mahjong Online | Switch | Arc System Works | Arc System Works | |
| Simple Man | Steam | | | |
| Simple Orbits | ItchIo | Jordan Kloosterman | | |
| Simple Outfit Creator | Roblox | | | |
| Simple Platformer Game | ItchIo | Sucholudek | | |
| Simple Portal | ItchIo | Santa Clara Games | | |
| Simple Prison | ItchIo | UselessMouth | | |
| Simple RTS | ItchIoSteam | GryWiktoraArowxkillereks | | |
| Simple Racing | Steam | | | |
| Simple Railroad | Steam | | | |
| Simple Sailing | Steam | | | |
| Simple Sliding Game | ItchIo | syawqy | | |
| Simple Sliding Game 2 | ItchIo | syawqy | | |
| Simple Soup Game | ItchIo | Kraud16 | | |
| Simple Spy | Steam | | | |
| Simple Story - Alex | Steam | | | |
| Simple Terrain Editor | ItchIo | JKUO | | |
| Simple Tetris | ItchIo | Supergoldapfel | | |
| Simple Undertale RP | Roblox | | | |
| Simple Wii Series Vol.1: The Minna de Kaato ReesuJP | Wii | D3 Publisher | D3 Publisher | |
| Simple Wii Series Vol.2: The Minna de Basu Duri TaikaiJP | Wii | D3 Publisher | D3 Publisher | |
| Simple Wii Series Vol.3: The Paatii KajinoJP | Wii | D3 Publisher | D3 Publisher | |
| Simple Wii Series Vol.4: The Shuutingu AkushonJP | Wii | D3 Publisher | D3 Publisher | |
| Simple Wii Series Vol.5: The Burokku KuzushiJP | Wii | D3 Publisher | D3 Publisher | |
| Simple Wii Series Vol.6: The Waiwai KonbattoJP | Wii | D3 Publisher | D3 Publisher | |
| Simple as Snow | ItchIo | castingdreams | | |
| Simple evolution Simulator | ItchIo | loco_games | | |
| SimpleMovie | Steam | | | |
| SimplePlanes | Steam | | | |
| SimplePlat | ItchIo | reelstank | | |
| SimpleQuest | ItchIo | Shamus Peveril | | |
| SimpleRockets | Steam | | | |
| SimpleRockets 2 | Steam | | | |
| Simplefield | Steam | | | |
| Simplex Mundi | ItchIoSteam | PixelKiln | | |
| Simply Chess | Steam | | | |
| Simply Hard Platformer | Steam | | | |
| Simply Parkour | Steam | | | |
| Simply Puzzles: Codewords | Steam | | | |
| Simply Puzzles: Junctions | Steam | | | |
| Simply Sorcery | Roblox | | | |
| SimplyTrivia | Steam | | | |
| Simpsons Arcade Game, The | ArcadeDOS | Novotrade International | Konami | |
| Simpsons, The: Bart vs. the Space Mutants | GameGear | Arc Developments | Flying Edge | |
| Simpsons, The: Bart vs. the World - Bart World JP | GameGear | Arc Developments | Flying EdgeAcclaim JP | |
| Simpsons, The: Bartman Meets Radioactive Man | GameGear | Teeny Weeny Games Ltd. | Flying Edge | |
| Simpsons: Bart vs the Space Mutants | ZXSpectrum | Arc Developments (Byron Nilsson, Paul Walker, Jonathan Dunn) | Ocean Software | |
| Simpsons: Bart vs. the Space Mutants | DOS | Imagineering | Acclaim EntertainmentOcean Software | |
| Simpsons: Bart vs. the Space Mutants, The | AmstradCPC | | Ocean Software | |
| Simpsons: Bart's House of Weirdness | DOS | Distinctive Software | Konami | |
| Sims 3, The | XBOX360 | Maxis | Electronic Arts | |
| Sims 3: Pets, The | XBOX360 | MaxisEdge of Reality | Electronic Arts | |
| Simson Tuningwerkstatt 3D | Steam | | | |
| Simulacra | SwitchXboxOne | Wales InteractiveKaigan Games | Wales Interactive | |
| Simulador Gravitacional | ItchIo | Felipe GoDoug Barreto | | |
| Simulador Jetpack! | Roblox | | | |
| Simulador Profesional de FĂştbol | DOS | Dinamic Software | Grupo Editorial Jackson | |
| Simulador Profesional de Tenis | DOSZXSpectrum | Alucine SoftAlucine Software (Francisco Javier Perez Aguilera, Ricardo Perez Aguilera, Armando Garcia) | Dinamic Software | |
| Simulador de Lasier Martins Tomando Choque na Festa da Uva | ItchIo | Caique Assis | | |
| Simulador de Porrada | ItchIo | Pectron | | |
| Simulated | ItchIo | namoooo | | |
| Simulateur de Capital | Steam | | | |
| Simulateur de Couteau | Roblox | | | |
| Simulateur de Gaufres | ItchIo | Fernando Sydenstricker C. | | |
| Simulateur de I Don't Feel So Good | Roblox | | | |
| Simulateur de Police | Steam | | | |
| Simulateur de Ruche | Roblox | | | |
| Simulateur de SMSđź’¬ | Roblox | | | |
| Simulateur de VĂ©hicules | Roblox | | | |
| Simulateur de boulangerie | Roblox | | | |
| Simulateur de bus | Roblox | | | |
| Simulateur de chasse au trésor | Roblox | | | |
| Simulateur de déneigement | Roblox | | | |
| Simulateur de frontière ( Border Simulator) | Roblox | | | |
| Simulateur de pĂŞche | Roblox | | | |
| Simulateur de sorciers ninjas | Roblox | | | |
| Simulateur de vol SFS | Roblox | | | |
| Simulateur du canal de Suez | Steam | | | |
| Simulateur d’exécution de vitesse | Roblox | | | |
| Simulation Pro Yakyuu | SNES | Hect | Hect | |
| Simulation Pro Yakyuu '99 | PS1 | Hect | Hect | |
| Simulation RPG Tsukuru | PS1SegaSaturn | Pegasus Japan | ASCII | |
| Simulation Simulator | ItchIo | Demizo | | |
| Simulation Zoo | PS1SegaSaturn | C&E Inc.Computer & Entertainment Inc.Alfa System | Soft Bank | |
| Simulation de bateau dynamique III | Roblox | | | |
| Simulation de catastrophe [DĂ©truire] | Roblox | | | |
| Simulation de pompiers | Roblox | | | |
| Simulator Simulator | ItchIo | Mr_Qqn | | |
| Simulators2021 | Steam | | | |
| Simulchess Prototype | ItchIo | Gunnar Clovis | | |
| Simutrans | Steam | | | |
| Sin | Windows | Ritual Entertainment | Activision | |
| Sin & Punishment: Star Successor | Wii | Treasure | Nintendo | |
| Sin Castle | Steam | | | |
| Sin Chess | Steam | | | |
| Sin Eater | ItchIo | Gutter | | |
| Sin and Punishment - Tsumi to Batsu: Hoshi no KeishĹŤshaJP | N64 | Treasure | Nintendo | |
| Sin; Vengeance | Steam | | | |
| SinSeed | Steam | | | |
| SinVR | Steam | | | |
| SinaRun | ItchIoSteam | Princesseuh | | |
| Sinbad Adventure wa Enomoto Kanako de Dou Desu ka | PS2 | Aruze | Nippon Amuse | |
| Sinbad and the Throne of the Falcon | DOS | Cinemaware | Cinemaware | |
| Since When Did I Have a Combat Butler?! | ItchIo | Tofu Sheets Visual | | |
| SincereMen | Steam | | | |
| Sinder | ItchIo | poxei | | |
| Sindibad: Chitei No Dai Makyu | PCEngine | | IGS | |
| Sine Mora | PS3SteamXBOX360 | Grasshopper ManufactureDigital Reality | Xbox Game Studios | |
| Sine Mora EX | SteamSwitchXboxOne | Digital RealityGrasshopper Manufacture | THQ Nordic | |
| Sine Requie: Snake Eyes | Steam | | | |
| Sine Wave City | Steam | | | |
| Sinewave | Steam | | | |
| Sinfonia [demo] | ItchIo | Caine | | |
| Sinful | ItchIo | Fenderbate | | |
| Sinful Eden | Steam | | | |
| Sing Party | WiiU | FreeStyleGamesNintendo SPD | Nintendo | |
| Sing4: The Hits Edition | Wii | Crave | Crave | |
| SingStar | PS2PS3 | London Studio | Sony Computer Entertainment | |
| SingStar '80s | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar '80s (EU version) | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar '90s | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar ABBA | PS2PS3 | London Studio | Sony Computer Entertainment | |
| SingStar Afrikaanse Treffers | PS3 | Sony London Studios | | |
| SingStar Afrikaansee Treffers | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar Amped | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar Anthems | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar Apres-Ski Party | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar Apres-Ski Party 2 | PS2PS3 | London Studio | Sony Computer Entertainment | |
| SingStar Back to the 80s | PS3 | London Studio | | |
| SingStar Bollywood | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar Boy Bands vs Girl Bands | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar Chart Hits | PS2PS3 | London Studio | Sony Computer Entertainment | |
| SingStar Chartbreaker | PS2PS3 | London Studio | Sony Computer Entertainment | |
| SingStar Country | PS2 | London Studio | Sony Computer Entertainment | |
| SingStar Dance | PS3 | London Studio | | |
| SingStar Danish Hits | PS3 | London Studio | | |
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