| Software Resources International | Developer | |
| Software Sorcery | DeveloperPublisher | |
| Software Sorcery (Gordon Fong) | Developer | |
| Software Storm | DeveloperPublisher | |
| Software Studios | Developer | |
| Software Studios (Alan Steel, Ed Hickman, Ian Bird) | Developer | |
| Software Studios (Bob Pape, Mark A Jones, Robert L Hylands) | Developer | |
| Software Studios (Dan Michek, Troy Lyndon, Scott Orr, John Cutter, Harald Seeley, Doug Barnett, Russell Lieblich) | Developer | |
| Software Studios (Keith Burkhill, Paul Hiley) | Developer | |
| Software Studios (Simon Freeman, Ian Bird) | Developer | |
| Software Toolworks | DeveloperPublisher | |
| Software Toolworks, Inc. | DeveloperPublisher | |
| Software by H | Publisher | |
| Softwave | Developer | |
| Softweaver | Developer | |
| Softwin Associates (Gordon Letwin) | Developer | |
| Softworks | Publisher | |
| Softzone | Developer | |
| Soggy Monster | Developer | |
| Soggybread Software | DeveloperPublisher | |
| Sogiciel | Publisher | |
| Sogna | DeveloperPublisher | |
| Soho Productions | Developer | |
| Sohrab Ismail‑Beigi | Developer | |
| Sohun | Developer | |
| SojaProduction | Developer | |
| Soji Yamakawa et al. | Developer | |
| Sokpop Collective | Developer | |
| Sokuaisushi | Developer | |
| Sokuzah | Developer | |
| Sol | Developer | |
| Sol Corporation | Developer | |
| SolWorks | Developer | |
| Solan | Publisher | |
| Solar Sail Games | Developer | |
| Solar Software | Publisher | |
| SolarLune | Developer | |
| SolarioGame | Developer | |
| Solarix | Developer | |
| Sold Out | Publisher | |
| Sold Out Sales & Marketing | Publisher | |
| Sold Out Software | Publisher | |
| Soldak Entertainment | DeveloperPublisher | |
| Soldnes | Developer | |
| Soleau Software | DeveloperPublisher | |
| Soleil | Developer | |
| Soleil Levant | Developer | |
| Soleil Ltd. | Developer | |
| Soleil Software | DeveloperPublisher | |
| Solid Clouds | Developer | |