| Encore Software, Inc, | Publisher | |
| Encore Software, Inc. | Developer | |
| Encore SoftwareNA | Publisher | |
| Encore, Inc. | Publisher | |
| EndCloudDigital | Developer | |
| End_Z_ | Developer | |
| Endemol | DeveloperPublisher | |
| EnderCow | Developer | |
| EnderPlayer | Developer | |
| Enderless | Developer | |
| Enderlinq | Developer | |
| Endermeister | Developer | |
| Enderplace | Developer | |
| Endflame | Developer | |
| Endgame Studios | Developer | |
| Endi Milojkoski | Developer | |
| Endless Code | Developer | |
| Endless-Studios | Developer | |
| Endlessfluff Games | Developer | |
| Endroad | Developer | |
| Endurance | Publisher | |
| Endurance Games | DeveloperPublisher | |
| Endurance Software | Publisher | |
| Endurion | Developer | |
| Endverse | Developer | |
| Enedee | Developer | |
| Eneme Entertainment | Developer | |
| Enerdyne | Publisher | |
| EnergyMilk | Developer | |
| Enes Ugur Sekerci | Developer | |
| Enezio Filho | Developer | |
| Enforker | Developer | |
| Enganmar | Developer | |
| Engine Software | DeveloperPublisher | |
| EngineGames | Developer | |
| EngineerKappa | Developer | |
| Engineering Animation, Inc. | Developer | |
| Engineface | Developer | |
| English Software | DeveloperPublisher | |
| Engon Games | Developer | |
| Enhance Games | DeveloperPublisher | |
| Enhex | Developer | |
| Enigami | Developer | |
| Enigma | Developer | |
| Enigma Dragons | Developer | |
| Enigma Software Developments (Hamish Rust, John Dalziel, Graeme Robertson, Pixar, Andy Brown, Martin McKenzie) | Developer | |
| Enigma Software Productions | Developer | |
| Enigma Software Productions S.L. | Developer | |
| Enigma Variations | DeveloperPublisher | |
| Enigma Variations (Andre Swann, Shaun McClure) | Developer | |
| Enigma Variations (Andrew Swann, Peter Tattersall, Shaun McClure, Paul Hiley) | Developer | |
| Enigma Variations (Damian Scattergood) | Developer | |
| Enigma Variations (David Bland, Paul Hiley) | Developer | |
| Enigma Variations (Fred O'Rourke, Robin Holman, Mick Hanrahan, Sean Conran) | Developer | |
| Enigma Variations (Ian Richards) | Developer | |
| Enigma Variations (Jason McGann, Robin Holman, Richard Naylor, Shaun McClure, Ben Daglish) | Developer | |
| Enigma Variations (Peter Tattersall) | Developer | |
| Enigma Variations (Shaun G McClure) | Developer | |
| Enigma Variations (Shaun McClure) | Developer | |
| Enigma Variations (Strawberry Jam, Shaun McClure) | Developer | |
| Enigma Variations Software | Publisher | |
| Eniko | Developer | |
| Enio Lotero | Developer | |
| Eniri | Developer | |
| Enity | Developer | |
| Enix | DeveloperPublisher | |
| Enix (JP) | Publisher | |
| Enix (NA) | Publisher | |
| Enix Corporation | DeveloperPublisher | |
| Enix JP | Publisher | |
| EnixJP | Publisher | |
| Enjmin Bundle | Developer | |
| Enjoy Gaming | DeveloperPublisher | |
| Enjoy GamingPAL | Publisher | |
| EnjoyUp | DeveloperPublisher | |
| EnjoyUp Games | DeveloperPublisher | |
| Enkian Games | Developer | |
| Enkord | DeveloperPublisher | |
| Enlades | Developer | |
| Enlight | DeveloperPublisher | |
| Enlight Software | DeveloperPublisher | |
| Enne | Developer | |
| Ennio Dal Farra | Developer | |
| Ennis Rook Bashe | Developer | |
| Ennui Studio | DeveloperPublisher | |
| Enola | Developer | |
| Enot487 | Developer | |
| Enreeper | Developer | |
| Enric Llagostera | Developer | |
| Enrico | Developer | |
| Enrique AM | Developer | |
| Enrique Alcazar | Developer | |
| Enrique Cervera | Developer | |
| Enrique Faustino Silvela | Developer | |
| Enrirossi | Developer | |
| Ensemble Studios | Developer | |
| EnsenaSoft | DeveloperPublisher | |
| Ensign Games | DeveloperPublisher | |
| Ensign Software | DeveloperPublisher | |
| Ent0Games | Developer | |
| EntenNugget | Developer | |
| Enter CTRL | Developer | |
| Enter Main Loop | Developer | |
| EnterTheVoid-x86 | Developer | |
| Enterbrain | DeveloperPublisher | |
| EnterbrainJP | Publisher | |
| Entergram | DeveloperPublisher | |
| Enterim | Developer | |
| Entertainment Enterprises, Ltd. | Publisher | |
| Entertainment Forge | Developer | |
| Entertainment Int | Developer | |
| Entertainment International | Developer | |
| Entertainment International UK | Publisher | |
| Entertainment Software Publishing | DeveloperPublisher | |
| Entertainment USA | Publisher | |
| Enthe | Developer | |
| Entity | Developer | |
| EntranceJew | Developer | |
| Entropic Arts | Developer | |
| Entropy Phi | Developer | |
| EntwicklerX | DeveloperPublisher | |
| Enya Games | Developer | |
| Enypsox | DeveloperPublisher | |
| Enzitoc | Developer | |
| EnzoUP | Developer | |
| Eokinyi35 | Developer | |
| Eolith | DeveloperPublisher | |
| Eon | Developer | |
| Eon Digital Entertainment | Publisher | |
| Eon Digital EntertainmentEU | Publisher | |
| Eon Software | Developer | |
| EonPAL | Publisher | |
| Ephoria Games | Developer | |
| EpiXR | Publisher | |
| EpiXR Games | DeveloperPublisher | |
| Epic | DeveloperPublisher | |
| Epic Blank Crew | Developer | |
| Epic Games | DeveloperPublisher | |
| Epic Interactive Strategy | DeveloperPublisher | |
| Epic LLama | Developer | |
| Epic Llama | Developer | |
| Epic MegaGames | DeveloperPublisher | |
| Epic Multimedia Group | Developer | |
| Epic Wolf Studio | Developer | |
| Epic/Sony Records JP | Publisher | |
| EpicBryan88 | Developer | |
| EpicCrownKing | Developer | |
| EpicLords Studios | Developer | |
| EpicRaisin | Developer | |
| EpicStudios | Developer | |
| EpicTastyPapple | Developer | |
| Epic_Gamer101 | Developer | |
| Epicenter Interactive | Developer | |
| Epicenter Studios | Developer | |
| Epicoro | Developer | |
| Epics | Developer | |
| Epiczsmo | Developer | |
| Epiin | Developer | |
| EpilogueSoft | Developer | |
| Epiphany Games | DeveloperPublisher | |
| EpiphanyG | Developer | |
| Epitasis Games | Developer | |
| Epixr | DeveloperPublisher | |
| Epixr Games | Publisher | |
| Epoch | DeveloperPublisher | |
| Epoch & SAS Sakata | Developer | |
| Epoch Co. | DeveloperPublisher | |
| Epoch Co. (JP) | Publisher | |
| Epoch Co., Ltd. | Publisher | |
| Epoch Co.JP | Publisher | |
| Epoch JP | Publisher | |
| Eponick's Lab | Developer | |
| Epos | Publisher | |
| Epos Corporation | Publisher | |
| Eppu Peltonen | Developer | |
| Epyx | DeveloperPublisher | |
| Equii | Developer | |
| Equilaterus Game Studios | Developer | |
| Equilibrium | Developer | |
| Equinox Digital Entertainment | Developer | |
| EquipoPsyche | Developer | |
| Equity | Publisher | |
| Equity Games | Publisher | |
| ErPabuls | Developer | |
| ErThu | Developer | |
| Erasmo Bellumat | Developer | |
| ErasmusCrowley | Developer | |
| Erathor_Noname | Developer | |
| Erbe Software | Publisher | |
| ErdemKaya | Developer | |
| Erdnusshonig | Developer | |
| EreMix | Developer | |
| Erendelous | Developer | |
| Erenor Games | Developer | |
| Erenso | Developer | |
| Erethan | Developer | |
| Ergo | Developer | |
| Ergurcay | Developer | |
| Eric | Developer | |
| Eric "Badspot" Hartman | Developer | |