| Mechabit | DeveloperPublisher | |
| Mechanic Arms | Developer | |
| Mechanical Head Studios | Developer | |
| MechanicsDriven | Developer | |
| Mechaspear Studios | Developer | |
| Mecinkari | Developer | |
| Mecko | DeveloperPublisher | |
| Med | Developer | |
| Med Systems | Publisher | |
| Med Systems Software | Publisher | |
| MedYaya | Developer | |
| Medalist International | Publisher | |
| Medallion Software | Publisher | |
| MediGuy | Developer | |
| Media 5 | DeveloperPublisher | |
| Media Art | Developer | |
| Media Entertainment | DeveloperPublisher | |
| Media Factory | DeveloperPublisher | |
| Media FactoryJP | Publisher | |
| Media Gallop | Developer | |
| Media Group | Publisher | |
| Media Kings | DeveloperPublisher | |
| Media Kite | Publisher | |
| Media KiteJP | Publisher | |
| Media Molecule | Developer | |
| Media Quest | Publisher | |
| Media Rings | DeveloperPublisher | |
| Media RingsJP | Publisher | |
| Media Sales & Licensing | DeveloperPublisher | |
| Media Vision | Developer | |
| Media Works | DeveloperPublisher | |
| Media.Vision | Developer | |
| Media5 | DeveloperPublisher | |
| MediaKite | DeveloperPublisher | |
| MediaQuest | DeveloperPublisher | |
| MediaWorks | DeveloperPublisher | |
| MediaWorks, Inc. | DeveloperPublisher | |
| Mediagenic | Publisher | |
| Mediagogo | DeveloperPublisher | |
| Mediamond Tmi | Publisher | |
| Mediamuse | Developer | |
| Mediarium | Developer | |
| Mediascape | Publisher | |
| Mediatech Game Studio | Developer | |
| Mediatonic | Developer | |
| Mediax | DeveloperPublisher | |
| Mediax Co., Ltd. | Developer | |
| MedicOnDuty | Developer | |
| MediocreMonty | Developer | |
| Medioza | DeveloperPublisher | |
| Meditator | Developer | |
| MedwidStudio | Developer | |
| Medza | Developer | |
| Meemog | Developer | |
| Meep | Developer | |
| MeepLeDoodle | Developer | |
| Mega Bite | Developer | |
| Mega Cat Studios | Developer | |
| Mega Dwarf Inc. | Developer | |
| Mega Enterprise | DeveloperPublisher | |
| Mega Man Maker Team | DeveloperPublisher | |
| Mega Power Games | Developer | |
| Mega Studios | Developer | |
| Mega Zeal Studio | Developer | |
| Mega-micro Computers (Art Canfil) | Developer | |
| Mega145 | Developer | |
| MegaBoss | Developer | |
| MegaCookie | Developer | |
| MegaCrit | Developer | |
| MegaFanZach | Developer | |
| MegaManfan334 | Developer | |
| MegaMax | Developer | |
| MegaPixel Studio | Developer | |
| MegaPixel Studios | Developer | |
| MegaProgramGuy | Developer | |
| MegaSaberEXE | Developer | |
| MegaSloth | Developer | |
| MegaSoft | Publisher | |
| MegaSoft Entertainment | Developer | |
| MegaXis | Developer | |
| Megableu | DeveloperPublisher | |
| Megabyte Media | Developer | |
| MegacomGames | Developer | |
| MegacrashREX | Developer | |
| Megacyber | DeveloperPublisher | |
| Megadodo Software | Publisher | |
| Megadream Software | Developer | |
| Megafuzz | DeveloperPublisher | |
| Megagon | Developer | |
| Megagon Industries | Developer | |
| Megahouse | DeveloperPublisher | |
| Megalodon | Developer | |
| Megalodon Corps | Developer | |
| Megami | DeveloperPublisher | |
| Megamon | Developer | |
| Megan | Developer | |
| Megan Carnes | Developer | |
| Megan Condis | Developer | |
| Megasoft | Developer | |
| Megasteakman | Developer | |