| Eclipse Software | Developer | |
| Eclipse Software Design | Developer | |
| Eclipsing_Binary | Developer | |
| EcoFilmes (now known as EcoPlay) | Publisher | |
| Ecole | DeveloperPublisher | |
| Ecole Software | DeveloperPublisher | |
| Ecole Software Corporation | Publisher | |
| Ecole SoftwareJP | Publisher | |
| Ecoludology Games | Developer | |
| Ecseco | DeveloperPublisher | |
| Ecseco Development | DeveloperPublisher | |
| Ecto | Developer | |
| Ectsatic | Developer | |
| Ed | Developer | |
| Ed Curtis-Sivess | Developer | |
| Ed Hickman | Developer | |
| Ed Hobbs | Developer | |
| Ed Jones | Developer | |
| Ed Key & David Kanaga | Developer | |
| Ed Knight | Developer | |
| Ed Naujokas | Developer | |
| Ed T. Toton III | Developer | |
| Ed Zaron | Developer | |
| Ed Zolnieryx | Developer | |
| EdLioni | Developer | |
| EdZ123 | Developer | |
| Edacth | Developer | |
| Edalbung | Developer | |
| Edamessiah | Developer | |
| Eddie | Developer | |
| Eddie Dombrower | Developer | |
| EddyA | Developer | |
| EddyGames | Developer | |
| Edelweiss | Developer | |
| Edelweiss303 | Developer | |
| Edelweiss_KR | Developer | |
| Eden | Developer | |
| Eden Entertainment | Developer | |
| Eden Entertainment Software | Developer | |
| Eden Games | Developer | |
| Eden Industries | DeveloperPublisher | |
| Eden Rave | Developer | |
| Eden Studios | Developer | |
| EdenDev | Developer | |
| EdenSoft | Developer | |
| Edenia_be | Developer | |
| Edern | Developer | |
| Edevjogos | Developer | |
| Edgar Belka | Developer | |
| Edgar J. | Developer | |