| Uneasy Game Studios | Developer | |
| Unenthullte | Developer | |
| Unenthuser | Developer | |
| Unepic Games | Publisher | |
| Unept | Developer | |
| UnevenPixelStudios | Developer | |
| Unexpected Development | Developer | |
| Unexpected Developments | Developer | |
| Unfinished Games | Developer | |
| Unfinished Pixel | DeveloperPublisher | |
| UnfinishedCircl | Developer | |
| Unfold Games | Developer | |
| Unforgotten | Developer | |
| Unformed | Developer | |
| Unfurl Games | Developer | |
| Ungrateful Dead | Developer | |
| Unholy_thoughts | Developer | |
| Uni Post Company Ltd | Publisher | |
| UniDot Studio | Developer | |
| UniGlow Entertainment | Developer | |
| Unibear Studio | Developer | |
| Unico | DeveloperPublisher | |
| Unico Electronics | Publisher | |
| Unicube | Developer | |
| Unicube Studios | Developer | |
| UnidayStudio | Developer | |
| Unidub | Developer | |
| Unimatrix Productions | Developer | |
| Union Logic | Developer | |
| Union Logic Software Publishing | Publisher | |
| Unipacc | Publisher | |
| Unique | Publisher | |
| Unique Development Studios | Developer | |
| Unisonshift | DeveloperPublisher | |
| Unistellar Industries, LLC | DeveloperPublisher | |
| Unit 4 Games | Developer | |
| Unit DTH Studios | DeveloperPublisher | |
| Unit02Games | Developer | |
| Unite Studios | Developer | |
| Unitech | Developer | |
| United Coders | Developer | |
| United Dreams | Developer | |
| United Front Games | Developer | |
| United Game Artists | DeveloperPublisher | |
| United Independent Entertainment | Publisher | |
| United Label | Publisher | |
| Unites | Publisher | |
| Unity Games | Publisher | |
| Unity Games Japan | Publisher | |
| Unity Ninja | Developer | |
| Unity Storm Dev | Developer | |
| Universal | DeveloperPublisher | |
| Universal Co. LTD | Publisher | |
| Universal Co. Ltd | Publisher | |
| Universal Interactive | Publisher | |
| Universal Interactive (USA Version) | Publisher | |
| Universal Interactive Studios | DeveloperPublisher | |
| Universal InteractiveEU,NA | Publisher | |
| Universal InteractiveNA,PAL | Publisher | |
| Universal InteractivePAL | Publisher | |
| Universal Music | Publisher | |
| Universal Space | Publisher | |
| Universal Spicy Boy | Developer | |
| Universal Studios | Publisher | |
| Universe Kaihatsu | Publisher | |
| University of Calgary Game Design Club | Developer | |
| University of Maine at Fort Kent | Developer | |
| University of Suffolk | Developer | |
| University of Texas at Austin: SAGA Lab | Developer | |
| Universo Ultra | Developer | |
| Universomo | Developer | |
| Unknown | DeveloperPublisher | |
| Unknown Changer | Developer | |
| Unknown Door Games | Developer | |
| Unknown Games | Developer | |
| Unknown Games Studio | Developer | |
| Unknown Synnapse | Developer | |
| Unknown Worlds | Developer | |
| Unknown Worlds Entertainment | DeveloperPublisher | |
| Unknown X | Developer | |
| UnknownLogicStudios | Developer | |
| UnknownOriginGames | Developer | |
| Unknowned | Developer | |
| Unlibox | Developer | |
| Unlimited Software | Developer | |
| Unlimited Trees | Developer | |
| UnlimitedPlayz | Developer | |
| Unlit team | Developer | |
| Unlucky Cat | Developer | |
| Unlucky-Alpaca | Developer | |
| Unnamed Fiasco Team | DeveloperPublisher | |
| Unnerved Studios | Developer | |
| Unplaytested | Developer | |
| Unreal Software | Developer | |
| Unreal Voodoo | Developer | |
| UnrealChan | Developer | |
| UnrealSpirit | Developer | |
| Unrealdreams | Developer | |
| Unreleased | Publisher | |
| Unruly Attractions | DeveloperPublisher | |
| Unsave Studios | Developer | |
| Unseen Interactive | Developer | |
| Unspielbar | Developer | |
| Unstable Games | Developer | |
| Unsung Warriors | Developer | |
| Untailo | Developer | |
| Untermann | Developer | |
| Unties | DeveloperPublisher | |
| Untitled Game Studio | Developer | |
| UntitledOutput | Developer | |
| Untitled_Games | Developer | |
| Untold Tales | Publisher | |
| Untouch | Developer | |
| Untralize Studio | Developer | |
| Untrustedlife | Developer | |
| Ununlucky Kitten | Developer | |
| Unusual Cadence | Developer | |
| UnvisibleDude | Developer | |
| Unwonted Studios | Developer | |
| UpTime | Publisher | |
| Upfall Studios | DeveloperPublisher | |
| Upheaval Entertainment | Developer | |
| UphillPromise | Developer | |
| Uplinked | Developer | |
| Upper Byte | Developer | |
| Upper Class Walrus | Developer | |
| Upper One Games | DeveloperPublisher | |
| UpperBit | Developer | |
| Uppercut Fames | Publisher | |
| Uppercut Games | DeveloperPublisher | |
| Uppon Hill | Developer | |
| Upside Down Bird | Developer | |
| Upstar | DeveloperPublisher | |
| Upstream Arcade | Developer | |
| Uptown Productions | DeveloperPublisher | |
| UrMum321 | Developer | |
| Uran | Developer | |
| Uranium Donut | Developer | |
| Urara-works | Developer | |
| Urban Development | Developer | |
| Urban Logic Games | Developer | |
| Urban Plant | DeveloperPublisher | |
| Urbanscan | Developer | |
| Urere | Developer | |
| Urethral Vector | Developer | |
| Uri Overton | Developer | |
| Urodela Games | Developer | |
| UrsiGames | Developer | |
| Urso Roxo | Developer | |
| Uruca Game Studio | Developer | |
| Us! | Developer | |
| UsamaSh | Developer | |
| Usamahsnakeeater | Developer | |
| Usanik | Developer | |
| Use | DeveloperPublisher | |
| Use Corporation | DeveloperPublisher | |
| Use Corporation JP | Publisher | |
| Useless Torch Games | Developer | |
| UselessMouth | Developer | |
| UselessTuna | Developer | |
| User0x7f | Developer | |
| User987 | Developer | |
| UserJoy Technology | Developer | |
| User_Userowich | Developer | |
| Usez | Developer | |
| UssProduction | Developer | |
| Ustwo | DeveloperPublisher | |
| Usualmanu | Developer | |
| Utdcus | Developer | |
| Uti Azulay | Developer | |
| Utility Function | Developer | |
| Utimate Senpai | Developer | |
| Utkarsh Raizada | Developer | |
| Utopia Game Studio | Developer | |
| Utopia Software | Developer | |
| Utopia Technologies | Developer | |
| Utopian World of Sandwiches | DeveloperPublisher | |
| UtopicLabs | Developer | |
| Utopixel | Developer | |
| UwUtankteam | Developer | |
| UyNad | Developer | |
| UzherGames | Developer | |
| Uzoo | Publisher | |
| U・Me Soft | DeveloperPublisher | |
| V Master | Developer | |
| V.K. | Developer | |
| V0LT | Developer | |
| V0odo0 | Developer | |
| V1 Interactive | Developer | |
| V1bhav20 | Developer | |
| V1|Exotic | Developer | |
| V3D Production | Developer | |
| V3derant | Developer | |
| V3rgi9ly | Developer | |
| V7 Entertainment | DeveloperPublisher | |
| VAC | Developer | |
| VAP | DeveloperPublisher | |
| VAP JP | Publisher | |
| VARLibraries | Developer | |
| VCC Entertainment | DeveloperPublisher | |