| Internet Helen | Developer | |
| Internet Janitor | Developer | |
| Interphase | Developer | |
| Interphase Technologies Inc. | DeveloperPublisher | |
| Interplay | DeveloperPublisher | |
| Interplay (PAL JP Versions) | Publisher | |
| Interplay Entertainment | DeveloperPublisher | |
| Interplay Entertainment (US)Gremlin Interactive (EU) | Publisher | |
| Interplay Entertainment Corp. | Publisher | |
| Interplay Entertainment EU | Publisher | |
| Interplay EntertainmentEU,NA | Publisher | |
| Interplay EntertainmentJP,NA | Publisher | |
| Interplay EntertainmentNA | Publisher | |
| Interplay EntertainmentPAL | Publisher | |
| Interplay NA/EU | Publisher | |
| Interplay Productions | DeveloperPublisher | |
| Interplay Productions (Michael Cranford) | Developer | |
| Interplay Productions (Rebecca Heineman, Bruce Schlickbernd, and Michael A. Stackpole) | Developer | |
| Interplay Value Products Division | Publisher | |
| InterplayNA | Publisher | |
| Interprog | Publisher | |
| Interroblank | Developer | |
| Interscan | Developer | |
| Interstel | DeveloperPublisher | |
| Interstel Corporation | DeveloperPublisher | |
| Inti Creates | DeveloperPublisher | |
| Intime Corporation | DeveloperPublisher | |
| Into A Dream | Developer | |
| IntraCorp | DeveloperPublisher | |
| IntracontrolStudios | Developer | |
| Intracorp | DeveloperPublisher | |
| Intracorp Entertainment | Publisher | |
| Intradom | Developer | |
| Intragames | DeveloperPublisher | |
| Intravenous Software | Developer | |
| Intrepid Games | Developer | |
| Intrepid Software | Publisher | |
| Intrepid Software Solutions, Inc. | Developer | |
| Intropy Games | DeveloperPublisher | |
| Introscopia | Developer | |
| Introversion Software | DeveloperPublisher | |
| Inu Games | Developer | |
| Inuplayz | Developer | |
| Invade Tech Software | Developer | |
| Invader Studios | DeveloperPublisher | |
| InvaderKazz | Developer | |
| Invalid State Games | Developer | |
| Inverge Studios | DeveloperPublisher | |
| Inverse Ontology | Developer | |
| Invert Mouse | Developer | |
| InvertMouse | Developer | |
| Inverted Games | Developer | |
| Inverted Hedgehog | Developer | |
| InvertedEarthTheory | Developer | |
| InvertedHuman | Developer | |
| Invex | DeveloperPublisher | |
| Invi Image | Publisher | |
| Invictus Games | DeveloperPublisher | |
| Invictus Games, Ltd. | Developer | |
| Invictus[citation needed] | Developer | |
| Invincible Cat | Developer | |
| Invincidude | Developer | |
| Invisible Collective | Publisher | |
| Invisible but Real Locomotive | Developer | |
| Involgamus | Developer | |
| Inzombi | Developer | |
| Iodine | Developer | |
| Iodine Dynamics | Developer | |
| Ioennir | Developer | |
| Iombra | Developer | |
| Ion Lands | Developer | |
| Ion Storm | Developer | |
| Ioncorupterx | Developer | |
| Ionescu Andrei | Developer | |
| Ionis Software International (Roger Danison) | Developer | |
| Iora Rua | Developer | |
| IoriBranford | Developer | |
| Iosys | DeveloperPublisher | |
| Iperurania Arts | Developer | |
| Iplayli | Developer | |
| Ippokratis | Developer | |
| Iramontes | Developer | |
| IratusLord | Developer | |
| Irem | DeveloperPublisher | |
| Irem (JP) | Publisher | |
| Irem (JP/EU) | Publisher | |
| Irem Corp. | Developer | |
| Irem JP/NA | Publisher | |
| Irem Software Engineering | DeveloperPublisher | |
| IremAS,JP,KO | Publisher | |
| IremJP | Publisher | |
| IremJP,KO | Publisher | |
| Irenburg | Developer | |
| Irene Lara | Developer | |
| Irgendwen | Developer | |
| Iridescent Industries | Developer | |
| Iridon | Developer | |
| Iridon Interactive AB | Developer | |
| Iris Dream | Developer | |
| Iris Idokogi | Developer | |