| SmashArtist | Developer | |
| SmashRiot | Developer | |
| Smashatron | Developer | |
| SmashedCrabStudio | Developer | |
| Smashing Pixels | Developer | |
| Smaxx | Developer | |
| Smcmax | Developer | |
| Smeeki | Developer | |
| SmeiCom | Publisher | |
| SmellyFrog | Developer | |
| Smile Axe | DeveloperPublisher | |
| Smile Soft | Publisher | |
| SmileBoom | DeveloperPublisher | |
| SmileStudios | Developer | |
| Smilebit | DeveloperPublisher | |
| Smilegate | Developer | |
| Smilesoft | Publisher | |
| Smiley Demon Games | Developer | |
| Smiley Wolfe | Developer | |
| Smiling Bag | Developer | |
| Smiling Buddha Games | DeveloperPublisher | |
| Smiling Dragon RPG Studios | Developer | |
| SmilingRider | Developer | |
| Smilodon | Developer | |
| SmithManC | Developer | |
| Smithn10 | Developer | |
| Smixbob | Developer | |
| Smn Mhmdy | Developer | |
| SmoLife | Developer | |
| SmoggyChips | Developer | |
| Smoke Fumus | Developer | |
| SmokeAndAsh | Developer | |
| SmokeSeller | Developer | |
| SmokeSomeFrogs | Developer | |
| Smokeyocity | Developer | |
| Smokin' Guns Productions | Developer | |
| Smoking Car Productions | Developer | |
| Smoking Gun Interactive | Developer | |
| Smoking Guns Production | Developer | |
| Smoking Wolf | Developer | |
| SmokyChambers | Developer | |
| Smol Beans Studio | Developer | |
| SmoothBrainDev | Developer | |
| SmoothCriminals | Developer | |
| Smore Hammer | Developer | |
| Smowete | Developer | |
| Smud Studios | Developer | |
| Smudged Cat Games | Developer | |
| Smumbo | Developer | |
| Snacking On! Software | Publisher | |
| Snagultoof | Developer | |
| Snail Game | Developer | |
| Snail Rhymer | Developer | |
| SnailSpace Games | Developer | |
| Snailovitch | Developer | |
| Snails Animation | Publisher | |
| Snails Arcade | Developer | |
| Snake Marmalade Studios | Developer | |
| SnakeSqueaker | Developer | |
| Snap Finger Click | DeveloperPublisher | |
| Snap Games | Developer | |
| SnapDragon Games | Developer | |
| Snapdragon Games | Developer | |
| Snapkick Studios | Developer | |
| Snapman | Developer | |
| SnappishStew | Developer | |
| Snappy Sloth | Developer | |
| Snapshot Games | DeveloperPublisher | |
| SnapstringGames | Developer | |
| Snatcho | Developer | |
| Snaylo | Developer | |
| Snazy Snake Studios | Developer | |
| Snazziful | Developer | |
| Sneaky Bastards | Developer | |
| Sneaky Pooch Studios | Developer | |
| Sneaky Sloth Studios | Developer | |
| SnedHlepPls | Developer | |
| SnekFriends | Developer | |
| SnepShark | Developer | |
| SnickSnack | Developer | |
| Sniffelur | Developer | |
| Snikkabo | Developer | |
| Snilebit | Developer | |
| Snipman | Developer | |
| Snipper Joey | Developer | |
| Snood World | Publisher | |
| Snoother | Developer | |
| Snoozy Kazoo | Developer | |
| Snophysh | Developer | |
| Snorkelhead | Developer | |
| Snorry0815 | Developer | |
| Snotax | Developer | |
| SnoutUp | Developer | |
| SnoutUp Games | Developer | |
| Snow | Developer | |
| Snow Day Software | DeveloperPublisher | |
| Snow Fox | Developer | |
| Snow Lion Entertainment | Developer | |
| SnowCito | Developer | |
| SnowOwl | Developer | |
| Snowball | Publisher | |
| Snowball.ru | Publisher | |
| Snowblind Studios | Developer | |
| Snowcastle Games | DeveloperPublisher | |
| Snowdrama | Developer | |
| Snowfall | Developer | |
| Snowflake Studios | Developer | |
| Snowflakes@gmx.at | Developer | |
| Snowforged | Developer | |
| Snowhaven Studios | Developer | |
| Snowhound Games | Developer | |
| Snowhydra Games | DeveloperPublisher | |
| Snowleaps | Developer | |
| Snowly Games | Developer | |
| Snowman | Publisher | |
| Snowrunner | DeveloperPublisher | |
| Snowrunner Productions | Publisher | |
| SnowyCocoon | Developer | |
| SnowyOwl | Developer | |
| SnowySierra | Developer | |
| Snowybit Software | Developer | |
| Snozbot | Developer | |
| Snuti | Developer | |
| Snylle | Developer | |
| Snöstorm Studio | Developer | |
| So Good Games | Developer | |
| So Romantic | Developer | |
| SoBad | Developer | |
| SoGoplay | Developer | |
| SoHoGames | Developer | |
| SoMa Play | Developer | |
| SoPlump | Developer | |
| Soap | Developer | |
| Soap Bubble Productions | Developer | |
| Soareverix | Developer | |
| Sobaka Studio | Developer | |
| Sobek Games | Developer | |
| Social Anvil UG (haftungsbeschränkt) | Developer | |
| SocialMeteorite | Developer | |
| Socialpoint | DeveloperPublisher | |
| Societa Daikanyama | DeveloperPublisher | |
| Société Pollene | Developer | |
| Socko! Entertainment | DeveloperPublisher | |
| Socksmakepeoplesexy.Net | Developer | |
| SodaDrinkerPro | Developer | |
| Sodigital | Publisher | |
| SodoDev | Developer | |
| Soedesco | DeveloperPublisher | |
| Sofa Bed Studios | Developer | |
| Sofa Squadron | Developer | |
| Sofdelux Studio | Developer | |
| Sofia Abatangelo | Developer | |
| Sofia Romualdo | Developer | |
| Sofie Magnusson | Developer | |
| SofieKSchmidt | Developer | |
| Sofix | DeveloperPublisher | |
| Sofronas | Developer | |
| Sofsource, Inc. | Publisher | |
| Soft Action | Developer | |
| Soft Bank | DeveloperPublisher | |
| Soft BankJP | Publisher | |
| Soft Enterprises | DeveloperPublisher | |
| Soft Hornet | Developer | |
| Soft House | Developer | |
| Soft House Aladdin | DeveloperPublisher | |
| Soft House Bon bee Bon Bon | DeveloperPublisher | |
| Soft Lava | Developer | |
| Soft Machine | Developer | |
| Soft Office | DeveloperPublisher | |
| Soft Option | Developer | |
| Soft Plan | DeveloperPublisher | |
| Soft Pro | Publisher | |
| Soft Pro International | Publisher | |
| Soft Studio Wing | DeveloperPublisher | |
| Soft Vision | DeveloperPublisher | |
| Soft Vision International / Coconuts Japan (JP) | Publisher | |
| Soft VisionJP | Publisher | |
| Soft-World | DeveloperPublisher | |
| Soft-World International | Publisher | |
| SoftBank | Publisher | |
| SoftColors | Developer | |
| SoftCore | Developer | |
| SoftFrame | Developer | |
| SoftGold Dotsoft | Publisher | |
| SoftKey | Publisher | |
| SoftLab Laboratories | DeveloperPublisher | |
| SoftLeafStudios | Developer | |
| SoftMax | DeveloperPublisher | |
| SoftServ, Inc. | Developer | |
| SoftSide | Publisher | |
| SoftStar | DeveloperPublisher | |
| Softalk | Publisher | |
| Softbank Corp. | Publisher | |
| Softdisk | DeveloperPublisher | |
| Softdisk (unreleased)[18] | Publisher | |
| Softdisk Publishing | Publisher | |
| Softeam | Developer | |
| Softek | Publisher | |
| Softek International (Christian F. Urquhart, Doc) | Developer | |
| Softel (Clive Wilson, Les Hogarth) | Developer | |