| Esmeralda | Developer | |
| Esmmazing | Developer | |
| Espii | Developer | |
| Espion Games | Developer | |
| Espirit Software Programs | Publisher | |
| Espressojet | Developer | |
| Esquadra | DeveloperPublisher | |
| Essay Games | Developer | |
| Essential Games | Developer | |
| Essential GamesEU | Publisher | |
| Essential GamesPAL | Publisher | |
| Esser & Hauffe GbR | Publisher | |
| Essometer | Developer | |
| EstacaoMarte | Developer | |
| Estacion Pi Y Diseno | DeveloperPublisher | |
| Esteban Grine | Developer | |
| Esteban Jauregui | Developer | |
| Estecka | Developer | |
| Estef_01 | Developer | |
| Estelle Martinez | Developer | |
| Ester Olsen | Developer | |
| EsthBeth | Developer | |
| Estraiti | Developer | |
| Estudio Egg | Developer | |
| Estudios Aquarela | Developer | |
| Estudios del Umo | Developer | |
| Estúdio Quinto | Developer | |
| Estúdio Vaca Roxa | Developer | |
| Etabubu | Developer | |
| Eternal Night Studios | Developer | |
| EternalDream | Developer | |
| Eternalian Studios | Developer | |
| EternityDev | Developer | |
| Ethan | Developer | |
| Ethan Loewald | Developer | |
| Ethan Nachreiner | Developer | |
| Ethan Zarov | Developer | |
| Ethan's Byproducts | Developer | |
| Ethan.Herron | Developer | |
| EthanA24 | Developer | |
| EthanChampy | Developer | |
| EthanKelly | Developer | |
| Ethanic Studios | Developer | |
| Ethel Chamomile | Developer | |
| Ethereal | Developer | |
| Ethereal Darkness Interactive | DeveloperPublisher | |
| EtherealCoffee | Developer | |
| Etherium-Apex | Developer | |
| Ethernalis | Developer | |
| Ethos | Developer | |
| Ethrea Dreams | Developer | |
| Eti Pazarlama ve Sanayi A.S. | Publisher | |
| Etn | Developer | |
| EtoDemerzel | Developer | |
| Etra (Etra Games) | Developer | |
| Etranges Libellules | Developer | |
| Etsa | Developer | |
| Etter Studio | Developer | |
| Etyen | Developer | |
| Etzwana | Developer | |
| Eufonie | Developer | |
| Eufrasio | Developer | |
| Eugen Systems | Developer | |
| Eugene | Developer | |
| Eugene Farrell | Developer | |
| Eugene Lazebny | Publisher | |
| Eugene Lin | Developer | |
| Eugene Messina | Developer | |
| Eugene Morris | Developer | |
| EugeneLoza | Developer | |
| EugeneSpacehead | Developer | |
| Eugenik | Developer | |
| Eugenio Barahona Marciel | Developer | |
| Eulalia Porto | Developer | |
| Euler Moises | Developer | |
| Euophrys | Developer | |
| Euphoria | Developer | |
| Euphoric Brothers | Developer | |
| Euriale | Developer | |
| Eurion11 | Developer | |
| EuroPress Software | DeveloperPublisher | |
| EuroVideo | Publisher | |
| EuroVideo Medien | Publisher | |
| Eurocom | DeveloperPublisher | |
| Eurocom Entertainment Software | DeveloperPublisher | |
| Eurocraft | Publisher | |
| Eurogold | Developer | |
| Europress | DeveloperPublisher | |
| Europress Software | DeveloperPublisher | |
| Eurosoft | DeveloperPublisher | |
| Eurovideo Medien | Publisher | |
| Eurritimia | Developer | |
| Euruanno00 | Developer | |
| Euskomi | Developer | |
| Eutechnyx | DeveloperPublisher | |
| Euvoltarei1 | Developer | |
| Ev1lbl0w | Developer | |
| Eva Abollivier | Developer | |
| Eva Khoury | Developer | |
| Eva Lee | Developer | |