| EREN45XD | Developer | |
| ERYNGI | Developer | |
| ESB Linux Custom Software Solutions | Developer | |
| ESCHER VISION | Developer | |
| ESD | Publisher | |
| ESD Games | Publisher | |
| ESP | DeveloperPublisher | |
| ESP (JP) | Publisher | |
| ESP Software | DeveloperPublisher | |
| ESP Software (John Wildsmith, Steven Day, Nick Jones) | Developer | |
| ESP SoftwareJP | Publisher | |
| ESTsoft Corp. | Developer | |
| ETAB Games | Developer | |
| ETK Works | Developer | |
| ETPA | Developer | |
| ETdoFresh | Developer | |
| ETechStudios | Developer | |
| EU | Publisher | |
| EU, CapcomJP | Publisher | |
| EU, TaitoJP | Publisher | |
| EU, Yuke'sJP | Publisher | |
| EU: 505 Games | Publisher | |
| EU: Avanquest | Publisher | |
| EU: Avanquest Software | Publisher | |
| EU: Bethesda Softworks | Publisher | |
| EU: Bigben Interactive | Publisher | |
| EU: Circle Entertainment | Publisher | |
| EU: DTP Entertainment | Publisher | |
| EU: Data Design Interactive | Publisher | |
| EU: Deep Silver | Publisher | |
| EU: Eko | Publisher | |
| EU: Empire Interactive | Publisher | |
| EU: Enjoy Gaming | Publisher | |
| EU: FunBox Media | Publisher | |
| EU: Funbox Media | Publisher | |
| EU: Ghostlight | Publisher | |
| EU: JoWooD Productions | Publisher | |
| EU: Joindots | Publisher | |
| EU: Koch Media | Publisher | |
| EU: Konami | Publisher | |
| EU: Marvelous Europe | Publisher | |
| EU: Maximum Games | Publisher | |
| EU: Metro3D | Publisher | |
| EU: Milestone srl | Publisher | |
| EU: Miracle Box Games | Developer | |
| EU: NIS America | Publisher | |
| EU: Namco Bandai Games | Publisher | |
| EU: Nobilis | Publisher | |
| EU: Nordcurrent | Publisher | |
| EU: Nordic Games | Publisher | |
| EU: Oxygen Games | Publisher | |
| EU: PQube | Publisher | |
| EU: Playlogic | Publisher | |
| EU: RTL Games | Publisher | |
| EU: Reef | Publisher | |
| EU: Rising Star Games | Publisher | |
| EU: Teyon | Publisher | |
| EU: Treva Entertainment | Publisher | |
| EU: Turtle Cream | Publisher | |
| EU: Zen United | Publisher | |
| EU: Zoo Digital Publishing | Publisher | |
| EU: Zushi Games | Publisher | |
| EVANGELINE PAPANICOLA | Developer | |
| EVC | Developer | |
| EVOLVE | Developer | |
| EX.ULT VIDEOTAINMENT | Developer | |
| EXE Create | Developer | |
| EXE-CREATE | Developer | |
| EXPVR | Developer | |
| EXRayo | Developer | |
| EZBake Games | Developer | |
| EZSD | Developer | |
| EZpurp | Developer | |
| E_net4 | Developer | |
| Eacrow | Developer | |
| Eadow | Developer | |
| Eae02 | Developer | |
| Eagle Berns and Holly Thomason | Developer | |
| Eagle Dynamics | Developer | |
| Eagle Interactive | Developer | |
| Eagle Marketing Corporation | Publisher | |
| EagleGames | Developer | |
| EaglePancake | Developer | |
| Eaglee | Developer | |
| Eagles | Developer | |
| Eaglesoft | Publisher | |
| Eamno | Developer | |
| Early Bird Press | Developer | |
| Early Morning Studio | DeveloperPublisher | |
| Earthborn | DeveloperPublisher | |
| Earthbound Books | Developer | |
| Earthdragon | Developer | |
| Earthlight Productions | Developer | |
| Earthly Delights | Developer | |
| Earthly Production | Developer | |
| Earthly Soft | Developer | |
| Earthmelon | Developer | |
| EaseGames | Developer | |
| East Cube | DeveloperPublisher | |
| East Entertainment Media | Publisher | |